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Web19 Mar 2024 · 基因敲入（过表达）是指利用转基因或同源重组等方式将外源功能基因或片段插入到基因组中，使其在细胞内持续发挥功能的技术。 传统转基因技术制备的小鼠，由 … WebSftpc-CreER;Scgb1a-CreER;Rosa-Tmtriple-heterozygous mice and injected them with a high dose of TMX (4 injections of 0.2 mg/g). This strategy labels a majority of AEC2s as well as …
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WebQiaquick pcr purification kit protocol RAS genes are commonly mutated in human cancer. Despite many possible mutations, individual cancer types often have a ‘tropism’ towards a … Web! 1!!!! SupplementalFigureS1,RelevanttoFigure1.Lineage 6labeledAEC1satsteady 6stateand only small clones are generated by AEC2s in* the adult lung in* the absence of
Web11 Jan 2024 · Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal degenerative lung disease of unknown etiology. Although in its final stages it implicates, in a reactive … WebSummaryThe lung’s gas exchange surface comprises thin alveolar type 1 (AT1) cells and cuboidal surfactant-secreting AT2 cells that are corrupted in some of the most common …
WebEfficient Transduction of Alveolar Type 2 Cells with Adeno-associated Virus for the Study of Lung Regeneration Web1 Jun 2014 · While SftpcCreER activity is active specifically in AEC2s in adult mice, it is possible that the constitutively active SPC-DTR transgene (expressed during embryonic …
WebFigure S4. Mesenchymal cell transplantation in BLM-injured lungs, Related to Figure 3 a, GFP+lung mesenchymal cells freshly isolated from GFP mice were intratracheally …
Web10 Jun 2013 · To do this, we generated Sftpc-CreER;Rosa26R-loxp-GFP-stop-loxp-diphtheria toxin A(abbreviated Rosa-DTA)/Rosa-Tmtriple heterozygous mice. A single low dose of … financepoint del cityok bad creditWeb028054 B6.129S- Sftpc tm1(cre/ERT2)Blh /J These knock-in Sftpc-CreER T2 mice express a tamoxifen-inducible Cre recombinase from the endogenous promoter/enhancer elements … gsn food potsWeb25 Oct 2024 · creER： 为cre重组酶与雌激素受体融合而成，可被tamoxifen激活。 如曾经的内皮Cre： MGI:3848982 ：Tg (Cdh5-cre/ER)1Rha【或写作 Cdh5 (PAC)-CreERT2】 … finance pool installationWebRESEARCH ARTICLE Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling Kari Brown,1 Alyssa Filuta,1 Marie-Gabrielle Ludwig,2 Klaus Seuwen,2 Julian … finance policy of a companyWeb2 Jun 2024 · Here, we show that human and mouse GPR116 control surfactant secretion and reuptake in alveolar type II (AT2) cells by regulating guanine nucleotide–binding … gsn foundationWebمرکزی صفحہ Proceedings of the National Academy of Sciences Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma finance poolingWebRelated documentation. Epigenetics Analysis and Integrated Analysis of Multiomics Data, Including Epigenetic Data, Using Artificial Intelligence in the Era of Precision Medicine finance polychain capital 320m