WebDec 2, 2024 · Bottom Line – Phenylephrine vs Pseudoephedrine Both drugs are decongestants used to treat nasal congestion because of colds, allergies, or sinus infections. However, a 2009 study done at the ENT … WebPhenylephrine acts mainly as an alpha-1-adrenergic receptor agonist with minimal beta-adrenergic action at therapeutic doses ; Pseudoephedrine activates both alpha and beta receptors, much like ephedrine ; Excessive stimulation of alpha- and beta-adrenergic receptors leads to central nervous system (CNS) and cardiovascular toxicity
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WebApr 1, 2024 · The decongestants, such as phenylephrine, and pseudoephedrine, produce a narrowing of blood vessels. This leads to clearing of nasal congestion, but it may also … WebJan 2, 2024 · Worse still, it tends to become more severe at bedtime. Unfortunately, oral nasal decongestants, such a Sudafed ( pseudoephedrine) and Sudafed PE ( phenylephrine), have stimulating effects for many individuals, and therefore may not be an option for you at bedtime. In fact, a variety of CNS (central nervous system) side effects have been ... full cast of first wives club
Antihistamine/Decongestant Combination (Oral Route)
WebDec 23, 2024 · Phenylephrine: It is safe to combine phenylephrine with Pseudoephedrine generally if you do not have high blood pressure. But, combining the two may increase … WebMar 9, 2014 · Pseudoephedrine constricts blood vessels in the nose and sinuses. This shrinks swelling and drains fluids, letting you breathe easier again. Unfortunately, the drug … WebMar 21, 2024 · Phenylephrine and alpha 1 adrenergic agonists are common ingredients in over-the-counter (OTC) cough and cold preparations. Phenylephrine is also available as nasal drops. ... Wezorek C DB, Krenzolok E. Pseudoephedrine: a prospective study to establish a toxic dose in children (abstract). Journal of toxicology Clinical toxicology … ginalis poole website