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Cxcl10 interferon gamma

C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein that in humans is encoded by the CXCL10 gene. C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family. See more The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. See more CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and See more CXCL9, CXCL10 and CXCL11 have proven to be valid biomarkers for the development of heart failure and left ventricular dysfunction, suggesting an underlining pathophysiological relation between levels of these chemokines and the development of … See more • Farber JM (March 1997). "Mig and IP-10: CXC chemokines that target lymphocytes". Journal of Leukocyte Biology. 61 (3): 246–57. doi:10.1002/jlb.61.3.246. PMID 9060447 See more The three-dimensional crystal structure of this chemokine has been determined under 3 different conditions to a resolution of up to 1.92 Å. The See more Baseline pre-treatment plasma levels of CXCL10 are elevated in patients chronically infected with hepatitis C virus (HCV) of genotypes … See more • Human C7 genome location and C7 gene details page in the UCSC Genome Browser. • Human CXCL10 genome location and CXCL10 gene details page in the UCSC Genome Browser See more WebJul 22, 2024 · Abstract. CXCL9 and CXCL10 can be produced by antigen-presenting cells (dendritic cells or macrophages) and by tumor cells. Hoch et al. demonstrated that …

CXCL10/CXCR3 signaling contributes to an inflammatory ... - eLife

WebIP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the … WebJun 27, 2011 · Interferon-gamma (IFN-γ)-inducible protein 10 (CXCL10, also called IP-10) was initially identified as a chemokine that is induced by IFN-γ and secreted by various cell types, such as monocytes, neutrophils, endothelial cells, keratinocytes, fibroblasts, mesenchymal cells, dendritic cells, and astrocytes [].CXCL10 is a 10-kDa protein and is … firming \u0026 tightening https://amgsgz.com

Synergistic Up-Regulation of CXCL10 by Virus and IFN γ in Human …

WebCXCL10 Protein, Rhesus macaque (His) MCE 国际站： CXCL10 Protein, Rhesus macaque (His) Synonyms: CXCL10; SCYB10C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10 WebGamma-IP10, C-X-C motif chemokine 10, INP10, 10 kDa interferon gamma-induced protein, Small-inducible cytokine B10, SCYB10, IP-10, CXCL10. Purification. Protein A or G purified from cell culture supernatant. Endotoxin level. Please contact with the lab for this information. Expression system. XtenCHO. WebGamma Interferon Inducible Protein 10. CXCL10 combined with cisplatin reduced tumor growth in LL/2 and CT26 tumor models more effectively, although the individual use of … euler hermes taiwan

Gene modulation and immunoregulatory roles of Interferonγ

Category:IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype …

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Cxcl10 interferon gamma

Targeting Chemokines and Chemokine Receptors in Multiple …

WebCXCL16 is a recently discovered multifaceted chemokine that has been shown not only to recruit activated T lymphocytes but also to play a direct role in the binding and phagocytosis of bacteria by professional antigen-presenting cells. In this study, WebExamining the endogenous expression of CXCL10 (IP10) THP1-Blue™ KI-IP10 pathway. THP1-Blue™ KI-IP10 cells have been designed to specifically examine the induction of the interferon-stimulated gene (ISG) IP10, also known as CXCL10, in response to bacterial and viral infection.Canonically, CXCL10 is known to be induced by the JAK/STAT signaling …

Cxcl10 interferon gamma

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WebObjective: Serum CXCL10 levels (sCXCL10) were measured in patients with active or inactive Graves' ophthalmopathy (GO). The effects of IFNgamma and TNFalpha … WebSep 29, 2024 · Interferon-γ (IFN-γ) is the sole member of the type II interferon family discovered almost 60 years ago. E. Frederick Wheelock was the first to describe IFN-γ as a phytohemagglutinin-induced virus inhibitor produced by white blood cells after they have been stimulated [].IFN-γ is a protein encoded by the IFNG gene, composed of two …

WebTarget Information. IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. WebTarget information. IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on ...

WebIP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. WebCXCL10 sera levels were three-fold higher in SSc vs. healthy controls, independent of subset and antibody positivity. Sildenafil treatment was associated with lower CXCL10 sera levels. ... Hfsmc and Hdfbs were simultaneously treated with Interferon-gamma (IFNγ) (1000 U/mL) + tumor necrosis factor (TNFα) (10 ng/mL) and scalar doses of ...

WebJul 29, 2024 · Interferon-gamma stimulates interferon-responsive macrophages to produce cytokine CXCL10. To explore the function of IFNRMs, we analysed the most characteristic genes according to subcellular locations and found that Ly6C and Ly6E were the most specific membrane proteins and CXCL10 was the most expressed secretory …

WebJan 15, 2024 · The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine receptor 3 (CXCR3). With a prototype function of directing temporal and spatial migration of activated T cells and natural killer cells, and inhibitory effects on … firming treatments for faceWebInterferon gamma-inducible protein (IP) 10 or CXCL10 is a member of the CXC chemokine family. It binds CXCR3 activating ERK1/2, p38/MAPK, JNK, and PI3-kinase/AKT … eulerian mass coordinateWebEnter the email address you signed up with and we'll email you a reset link. eulerian path in cWebTarget Information. IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on ... euler hermes thailandWebApr 24, 2024 · C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 are produced in response to interferon-γ (IFN-γ) and trigger inflammation with the accumulation of … eulerian vs lagrangian reference systemsWebIP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. euler identity complexWebIt has been hypothesized that interferon (IFN) alpha and beta cause autoimmune thyroid dysfunctions by changing the Th1/Th2 balance, but the mechanisms involved are not yet … eulerian vs lagrangian approach